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Hydrocodone: Complete Drug Guide and Instructions
Learn about the medicinal uses, mode of action, dosage forms, warnings, and side effects of Hydrocodone before you buy Hydrocodone online. The Food and Drug Administration (FDA) approved the sale of this medication in the US in 1943.
Basic Details
Hydrocodone, also referred to as dihydrocodeinone, is an opioid medication commonly used to alleviate pain and reduce coughing. Brand names include Lortab®, Lorcet-HD®, Hycodan®, Vicoprofen®, Norco®, and Vicodin®. It is typically prescribed as a combination of acetaminophen/hydrocodone or ibuprofen/hydrocodone for severe pain or with homatropine methylbromide to reduce cough.
A long-acting version, Zohydro ER, can treat severe, prolonged pain. Hydrocodone is a Schedule II controlled substance in the United States.
The extended-release form of hydrocodone was approved for medical use in the United States in 2013. As of 2010, the United States accounted for 99% of the global supply of Hydrocodone. In 2018, it was the 402nd most commonly prescribed drug in the US, with over 400,000 prescriptions. Hydrocodone is a semi-synthetic opioid derived from Codeine or, less frequently, Thebaine.
Who Can Take Hydrocodone?
Hydrocodone is typically used to ease pain because it contains substances that calm the body. It works by changing how the brain and nervous system process pain. Hydrocodone is also effective as a cough suppressant.
How Does Hydrocodone Work?
Hydrocodone belongs to the class of drugs known as narcotic analgesics. It acts on the central nervous system (CNS) to relieve pain and prevent coughing. The medication blocks pain impulses from reaching the brain, providing relief.
The half-life of Hydrocodone is 4 to 6 hours, with peak serum concentrations reached after 1 hour. About 85% of the drug is eliminated through urine within 24 hours. In healthy adult males, the half-life of Hydrocodone is approximately 3 hours.
Hydrocodone Warnings and Precautions
Before you order Hydrocodone online, consider these warnings and precautions:
- Alcohol Interaction: The effects of Hydrocodone are intensified when combined with alcohol, potentially leading to hazardous adverse effects, including a deadly overdose.
- Adrenal Gland Disorders: Consult your doctor if you experience skin darkening, diarrhea, dizziness, lack of appetite, nausea, skin rash, or weakness.
- Pregnancy: Using this medication during pregnancy may result in withdrawal symptoms in newborns. Inform your doctor if your infant exhibits withdrawal symptoms.
- Allergic Reactions: Hydrocodone can cause anaphylaxis, a life-threatening allergic reaction that requires immediate medical attention.
- Constipation: Hydrocodone may induce severe constipation. Follow your doctor’s instructions to prevent serious complications.
How to Take Hydrocodone
Take Hydrocodone exactly as prescribed by your doctor. Do not exceed the prescribed dose or duration. This is especially crucial for the elderly, who may be more susceptible to the effects of pain medications. Misuse can lead to habit formation or overdose.
- Extended-Release Tablets or Pills: These are prescribed for opioid-tolerant individuals. Confirm with your doctor if you are opioid-tolerant before using this medication. Take Hydrocodone daily, with or without food, and swallow the extended-release pill whole. Do not crush, split, chew, or dissolve it.
- Dosage Schedule: Take the medication at the same time each day. Do not give this medicine to children unless prescribed by a doctor.
- Gradual Discontinuation: Do not abruptly stop using Hydrocodone. Consult your doctor to reduce the dosage gradually.
Hydrocodone Dosage Information
Hydrocodone is available in various forms and strengths:
- Extended-Release Capsules (Zohydro ER): Take 10mg orally every 12 hours.
- Extended-Release Tablets (Hysingla ER): Take 20mg orally every 24 hours.
A high dose of Hydrocodone (more than 40mg per tablet) is not recommended for mild pain relief.
Possible Risks of Taking Hydrocodone
Excessive use of Hydrocodone can lead to these side effects:
- Nausea
- Constipation
- Skin redness
- Mood swings
- Headache
- Loss of appetite
- Blurred vision
- Confusion
- Dry mouth
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